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Download e-book for iPad: Cognitive-Affective Neuroscience of Depression and Anxiety by Dan J Stein

By Dan J Stein

ISBN-10: 0203676661

ISBN-13: 9780203676660

ISBN-10: 1841841005

ISBN-13: 9781841841007

ISBN-10: 1841843032

ISBN-13: 9781841843032

Info on melancholy and anxiousness problems now spans various fields from molecular neuroscience, via cognitive and affective technology, and directly to evolutionary psychology. the writer right here integrates this paintings into one quantity, supplying the clinician with a theoretical synthesis in addition to an invaluable functional framework. Cognitive-Affective Neuroscience of melancholy and anxiousness issues is helping pros in those a number of fields to control sufferers with significant melancholy, generalized anxiousness sickness, obsessive-compulsive sickness, panic illness, post-traumatic tension sickness and social nervousness affliction. Neuroscientists, neurologists, pharmacologists, psychiatrists and psychological overall healthiness practitioners will take advantage of this article

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Extra info for Cognitive-Affective Neuroscience of Depression and Anxiety Disorders

Sample text

Obsessions are intrusive thoughts, ideas, or images that increase anxiety, whereas compulsions are repetitive rituals or mental actions performed in response to obsessions in order to decrease anxiety. 2) and across cultures (Stein and Rapoport, 1996). Despite this homogeneity, there have been increasing attempts to further the understanding and treatment of OCD by specifying different subgroups. There is some evidence, for example, that the various symptoms of OCD can be mapped onto a four-factor solution, with each symptom factor being mediated by somewhat different neurobiological factors (Leckman et al, 1997).

In addition, PET scanning during anxious anticipation in normals (Reiman et al, 1989a), and during lactate-induced panic attacks in panic disorder patients (Reiman et al, 1989b) both demonstrated increased activity in paralimbic regions (temporal poles). 1). An early study suggested that only panic disorder patients susceptible to lactate-induced panic had abnormal asymmetry of a parahippocampal region at rest (Reiman et al, 1986). Subsequent functional imaging studies have confirmed dysfunctions of hippocampus or parahippocampal regions in panic disorder, although the precise abnormalities documented have not always been consistent (Gorman et al, 2000).

2Typical obsessions and consequent compulsions in OCD. 3Putative obsessive-compulsive spectrum disorders. presence of comorbid tics in OCD appears to have specific treatment implications. 3). Although controversy remains about which disorders belong to this spectrum, a number of conditions share considerable phenomenological and neurobiological overlap with OCD. In particular, several disorders characterized by intrusive repetitive symptoms show a selective response to serotonin reup take inhibitors (SRIs) in comparison with noradrenaline reuptake inhibitors (NRIs); these include OCD itself, body dysmorphic disorder, possibly olfactory reference syndrome, hypochondriasis, trichotillomania, and obsessive-compulsive symptoms in Tourette’s 27 syndrome (TS) and autism.

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Cognitive-Affective Neuroscience of Depression and Anxiety Disorders by Dan J Stein


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